E-Signatures using Topaz signature pads are only currently supported inside of Internet Explorer 11.
Social Solutions is working on making Topaz browser extensions work inside of ETO. This will allow Topaz and ETO to work together in Chrome and other browsers.
Please up vote the idea in our portal "Electronic Signatures in non-IE browsers" and check back on this page and our release notes for updates.
E-Signature using a mouse is compatible with iPads, Chrome on a Desktop, Internet Explorer 11. For more on our browser compatibility please see this article.
If you and your team are experiencing this issue, please report it to our support team at email@example.com